| 19 February 2021 | ||||||
| 20:00 | Wolverhampton Wanderers |  | 1:0 |  | Leeds United |  |
| 20 February 2021 | ||||||
| 12:30 | Southampton |  | 1:1 |  | Chelsea | |
| 15:00 | Burnley |  | 0:0 |  | WBA | |
| 17:30 | Liverpool |  | 0:2 |  | Everton | |
| 20:00 | Fulham |  | 1:0 |  | Sheffield United | |
| 21 February 2021 | ||||||
| 12:00 | West Ham United |  | 2:1 |  | Tottenham Hotspur | |
| 14:05 | Aston Villa |  | 1:2 |  | Leicester City | |
| 16:30 | Arsenal |  | 0:1 |  | Manchester City | |
| 19:00 | Manchester United |  | 3:1 |  | Newcastle United | |
| 22 February 2021 | ||||||
| 20:00 | Brighton |  | 1:2 |  | Crystal Palace | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Manchester City | 24 | 17 | 5 | 2 | 47:14 | 56 |
| 2. |  | Manchester United | 25 | 14 | 7 | 4 | 53:32 | 49 |
| 3. |  | Leicester City | 25 | 15 | 4 | 6 | 44:27 | 49 |
| 4. |  | West Ham United | 25 | 13 | 6 | 6 | 39:29 | 45 |
| 5. |  | Chelsea | 25 | 12 | 7 | 6 | 41:25 | 43 |
| 6. |  | Liverpool | 25 | 11 | 7 | 7 | 45:34 | 40 |
| 7. |  | Everton | 23 | 12 | 4 | 7 | 36:30 | 40 |
| 8. |  | Aston Villa | 23 | 11 | 3 | 9 | 37:26 | 36 |
| 9. |  | Tottenham Hotspur | 24 | 10 | 6 | 8 | 37:27 | 36 |
| 10. |  | Arsenal | 25 | 10 | 4 | 11 | 31:26 | 34 |
| 11. |  | Wolverhampton Wanderers | 25 | 9 | 6 | 10 | 26:32 | 33 |
| 12. |  | Leeds United | 24 | 10 | 2 | 12 | 40:43 | 32 |
| 13. |  | Crystal Palace | 25 | 9 | 5 | 11 | 29:43 | 32 |
| 14. |  | Southampton | 24 | 8 | 6 | 10 | 31:40 | 30 |
| 15. |  | Burnley | 24 | 7 | 6 | 11 | 17:29 | 27 |
| 16. |  | Brighton | 25 | 5 | 11 | 9 | 26:32 | 26 |
| 17. |  | Newcastle United | 25 | 7 | 4 | 14 | 26:43 | 25 |
| 18. |  | Fulham | 24 | 4 | 9 | 11 | 20:31 | 21 |
| 19. |  | WBA | 25 | 2 | 8 | 15 | 19:55 | 14 |
| 20. |  | Sheffield United | 25 | 3 | 2 | 20 | 15:41 | 11 |
Stadium: Falmer Stadium (Brighton and Hove)
Season: 2020-21, 25 round, 2021-02-22 20:00
1:2
(0:1)
| 28' |  | 0:1 | Jean-Philippe Mateta |
| 53' |  | Dan Burn | |
| 55' | | 1:1 | Joël Veltman |
| 84' | | Joël Veltman | |
| 90+5' | | 1:2 | Christian Benteke |
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