| 21 August 2021 | ||||||
| 12:30 | Liverpool |  | 2:0 |  | Burnley |  |
| 15:00 | Aston Villa |  | 2:0 |  | Newcastle United | |
| 15:00 | Manchester City |  | 5:0 |  | Norwich City | |
| 17:30 | Brighton |  | 2:0 |  | Watford | |
| 22 August 2021 | ||||||
| 14:00 | Wolverhampton Wanderers |  | 0:1 |  | Tottenham Hotspur | |
| 16:30 | Arsenal |  | 0:2 |  | Chelsea | |
| 23 August 2021 | ||||||
| 20:00 | West Ham United |  | 4:1 |  | Leicester City | |
| 27 August 2022 | ||||||
| 12:30 | Southampton |  | 1:1 |  | Manchester United | |
| 30 August 2022 | ||||||
| 19:30 | Crystal Palace |  | 0:0 |  | Brentford | |
| 20:00 | Leeds United |  | 2:2 |  | Everton | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | West Ham United | 2 | 2 | 0 | 0 | 8:3 | 6 |
| 2. |  | Chelsea | 2 | 2 | 0 | 0 | 5:0 | 6 |
| 3. |  | Liverpool | 2 | 2 | 0 | 0 | 5:0 | 6 |
| 4. |  | Brighton | 2 | 2 | 0 | 0 | 4:1 | 6 |
| 5. |  | Tottenham Hotspur | 2 | 2 | 0 | 0 | 2:0 | 6 |
| 6. |  | Manchester United | 2 | 1 | 1 | 0 | 6:2 | 4 |
| 7. |  | Everton | 2 | 1 | 1 | 0 | 5:3 | 4 |
| 8. |  | Brentford | 2 | 1 | 1 | 0 | 2:0 | 4 |
| 9. |  | Manchester City | 2 | 1 | 0 | 1 | 5:1 | 3 |
| 10. |  | Aston Villa | 2 | 1 | 0 | 1 | 4:3 | 3 |
| 11. |  | Watford | 2 | 1 | 0 | 1 | 3:4 | 3 |
| 12. |  | Leicester City | 2 | 1 | 0 | 1 | 2:4 | 3 |
| 13. |  | Southampton | 2 | 0 | 1 | 1 | 2:4 | 1 |
| 14. |  | Crystal Palace | 2 | 0 | 1 | 1 | 0:3 | 1 |
| 15. |  | Leeds United | 2 | 0 | 1 | 1 | 3:7 | 1 |
| 16. |  | Wolverhampton Wanderers | 2 | 0 | 0 | 2 | 0:2 | 0 |
| 17. |  | Burnley | 2 | 0 | 0 | 2 | 1:4 | 0 |
| 18. |  | Newcastle United | 2 | 0 | 0 | 2 | 2:6 | 0 |
| 19. |  | Arsenal | 2 | 0 | 0 | 2 | 0:4 | 0 |
| 20. |  | Norwich City | 2 | 0 | 0 | 2 | 0:8 | 0 |
Stadium: Molineux (Wolverhampton), 30,368 audience (95% full)
Season: 2021-22, 2 round, 2021-08-22 14:00
0:1
(0:1)
| 9' |  | 0:1 | Dele Alli |
| 38' |  | Japhet Tanganga | |
| 44' | | Oliver Skipp | |
| 57' | | Raúl Jiménez | |
| 86' | | Pierre Emile Hojbjerg | |
| 90+1' | | Harry Kane |
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