| 05 March 2022 | ||||||
| 12:30 | Leicester City |  | 1:0 |  | Leeds United |  |
| 15:00 | Aston Villa |  | 4:0 |  | Southampton | |
| 15:00 | Burnley |  | 0:4 |  | Chelsea | |
| 15:00 | Newcastle United |  | 2:1 |  | Brighton | |
| 15:00 | Norwich City |  | 1:3 |  | Brentford | |
| 15:00 | Wolverhampton Wanderers |  | 0:2 |  | Crystal Palace | |
| 17:30 | Liverpool |  | 1:0 |  | West Ham United | |
| 06 March 2022 | ||||||
| 14:00 | Watford |  | 2:3 |  | Arsenal | |
| 16:30 | Manchester City |  | 4:1 |  | Manchester United | |
| 07 March 2022 | ||||||
| 20:00 | Tottenham Hotspur |  | 5:0 |  | Everton | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Manchester City | 28 | 22 | 3 | 3 | 68:18 | 69 |
| 2. |  | Liverpool | 27 | 19 | 6 | 2 | 71:20 | 63 |
| 3. |  | Chelsea | 26 | 15 | 8 | 3 | 53:18 | 53 |
| 4. |  | Arsenal | 25 | 15 | 3 | 7 | 41:29 | 48 |
| 5. |  | Manchester United | 28 | 13 | 8 | 7 | 45:38 | 47 |
| 6. |  | West Ham United | 28 | 13 | 6 | 9 | 46:35 | 45 |
| 7. |  | Tottenham Hotspur | 26 | 14 | 3 | 9 | 40:32 | 45 |
| 8. |  | Wolverhampton Wanderers | 27 | 12 | 4 | 11 | 24:23 | 40 |
| 9. |  | Southampton | 27 | 8 | 11 | 8 | 34:41 | 35 |
| 10. |  | Crystal Palace | 28 | 7 | 12 | 9 | 39:38 | 33 |
| 11. |  | Aston Villa | 26 | 10 | 3 | 13 | 37:37 | 33 |
| 12. |  | Brighton | 27 | 7 | 12 | 8 | 26:32 | 33 |
| 13. |  | Leicester City | 24 | 8 | 6 | 10 | 38:43 | 30 |
| 14. |  | Newcastle United | 26 | 6 | 10 | 10 | 30:46 | 28 |
| 15. |  | Brentford | 28 | 7 | 6 | 15 | 30:45 | 27 |
| 16. |  | Leeds United | 27 | 5 | 8 | 14 | 29:61 | 23 |
| 17. |  | Everton | 25 | 6 | 4 | 15 | 28:46 | 22 |
| 18. |  | Burnley | 25 | 3 | 12 | 10 | 22:34 | 21 |
| 19. |  | Watford | 27 | 5 | 4 | 18 | 27:50 | 19 |
| 20. |  | Norwich City | 27 | 4 | 5 | 18 | 16:58 | 17 |
Stadium: Tottenham Hotspur (London), 59,647 audience (96% full)
Season: 2021-22, 28 round, 2022-03-07 20:00
5:0
(3:0)
| 14' |  | 1:0 | Michael Keane |
| 17' |  | 2:0 | Son Heung-min |
| 24' |  | Son Heung-min | |
| 30' | | Cristian Romero | |
| 37' | | 3:0 | Harry Kane |
| 46' | | 4:0 | Sergio Reguilón |
| 55' | | 5:0 | Harry Kane |
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