| 10 September 2016 | ||||||
| 12:30 | Manchester United |  | 1:2 |  | Manchester City |  |
| 15:00 | Bournemouth |  | 1:0 |  | WBA | |
| 15:00 | Arsenal |  | 2:1 |  | Southampton | |
| 15:00 | Burnley |  | 1:1 |  | Hull City | |
| 15:00 | Middlesbrough |  | 1:2 |  | Crystal Palace | |
| 15:00 | Stoke City |  | 0:4 |  | Tottenham Hotspur | |
| 15:00 | West Ham United |  | 2:4 |  | Watford | |
| 17:30 | Liverpool |  | 4:1 |  | Leicester City | |
| 11 September 2016 | ||||||
| 16:00 | Swansea City |  | 2:2 |  | Chelsea | |
| 12 September 2016 | ||||||
| 20:00 | Sunderland |  | 0:3 |  | Everton | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Manchester City | 4 | 4 | 0 | 0 | 11:4 | 12 |
| 2. |  | Chelsea | 4 | 3 | 1 | 0 | 9:4 | 10 |
| 3. |  | Everton | 4 | 3 | 1 | 0 | 7:2 | 10 |
| 4. |  | Manchester United | 4 | 3 | 0 | 1 | 7:3 | 9 |
| 5. |  | Tottenham Hotspur | 4 | 2 | 2 | 0 | 7:2 | 8 |
| 6. |  | Liverpool | 4 | 2 | 1 | 1 | 9:7 | 7 |
| 7. |  | Arsenal | 4 | 2 | 1 | 1 | 8:6 | 7 |
| 8. |  | Hull City | 4 | 2 | 1 | 1 | 5:3 | 7 |
| 9. |  | Middlesbrough | 4 | 1 | 2 | 1 | 4:4 | 5 |
| 10. |  | Watford | 4 | 1 | 1 | 2 | 7:8 | 4 |
| 11. |  | Crystal Palace | 4 | 1 | 1 | 2 | 3:4 | 4 |
| 12. |  | WBA | 4 | 1 | 1 | 2 | 2:3 | 4 |
| 13. |  | Swansea City | 4 | 1 | 1 | 2 | 4:6 | 4 |
| 14. |  | Bournemouth | 4 | 1 | 1 | 2 | 3:5 | 4 |
| 15. |  | Burnley | 4 | 1 | 1 | 2 | 3:5 | 4 |
| 16. |  | Leicester City | 4 | 1 | 1 | 2 | 4:7 | 4 |
| 17. |  | West Ham United | 4 | 1 | 0 | 3 | 5:9 | 3 |
| 18. |  | Southampton | 4 | 0 | 2 | 2 | 3:6 | 2 |
| 19. |  | Sunderland | 4 | 0 | 1 | 3 | 3:8 | 1 |
| 20. |  | Stoke City | 4 | 0 | 1 | 3 | 2:10 | 1 |
Stadium: London Stadium (London), 56,974 audience (95% full)
Season: 2016-17, 4 round, 2016-09-10 15:00
2:4
(2:2)
| 5' |  | 1:0 | Michail Antonio |
| 33' | | 2:0 | Michail Antonio |
| 41' | | 2:1 | Odion Ighalo |
| 45' | | 2:2 | Troy Deeney |
| 53' | | 2:3 | Étienne Capoue |
| 64' | | 2:4 | José Holebas |
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