| 18 January 2022 | ||||||
| 20:00 | Brighton |  | 1:1 |  | Chelsea |  |
| 08 February 2022 | ||||||
| 19:45 | West Ham United |  | 1:0 |  | Watford | |
| 19:45 | Newcastle United |  | 3:1 |  | Everton | |
| 20:00 | Burnley |  | 1:1 |  | Manchester United | |
| 09 February 2022 | ||||||
| 19:45 | Norwich City |  | 1:1 |  | Crystal Palace | |
| 19:45 | Manchester City |  | 2:0 |  | Brentford | |
| 20:00 | Aston Villa |  | 3:3 |  | Leeds United | |
| 10 February 2022 | ||||||
| 19:45 | Wolverhampton Wanderers |  | 0:1 |  | Arsenal | |
| 19:45 | Liverpool |  | 2:0 |  | Leicester City | |
| 06 August 2022 | ||||||
| 15:00 | Tottenham Hotspur |  | 2:3 |  | Southampton | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Manchester City | 24 | 19 | 3 | 2 | 57:14 | 60 |
| 2. |  | Liverpool | 23 | 15 | 6 | 2 | 60:19 | 51 |
| 3. |  | Chelsea | 24 | 13 | 8 | 3 | 48:18 | 47 |
| 4. |  | West Ham United | 24 | 12 | 4 | 8 | 42:31 | 40 |
| 5. |  | Arsenal | 22 | 12 | 3 | 7 | 34:25 | 39 |
| 6. |  | Manchester United | 23 | 11 | 6 | 6 | 37:31 | 39 |
| 7. |  | Tottenham Hotspur | 21 | 11 | 3 | 7 | 28:27 | 36 |
| 8. |  | Wolverhampton Wanderers | 22 | 10 | 4 | 8 | 19:17 | 34 |
| 9. |  | Brighton | 22 | 6 | 12 | 4 | 23:23 | 30 |
| 10. |  | Southampton | 23 | 6 | 10 | 7 | 29:36 | 28 |
| 11. |  | Aston Villa | 22 | 8 | 3 | 11 | 31:35 | 27 |
| 12. |  | Leicester City | 21 | 7 | 5 | 9 | 34:39 | 26 |
| 13. |  | Crystal Palace | 23 | 5 | 10 | 8 | 31:34 | 25 |
| 14. |  | Brentford | 24 | 6 | 5 | 13 | 26:40 | 23 |
| 15. |  | Leeds United | 22 | 5 | 8 | 9 | 27:43 | 23 |
| 16. |  | Everton | 21 | 5 | 4 | 12 | 24:37 | 19 |
| 17. |  | Newcastle United | 22 | 3 | 9 | 10 | 24:44 | 18 |
| 18. |  | Norwich City | 23 | 4 | 5 | 14 | 14:46 | 17 |
| 19. |  | Watford | 22 | 4 | 3 | 15 | 23:41 | 15 |
| 20. |  | Burnley | 20 | 1 | 11 | 8 | 17:28 | 14 |
Stadium: Molineux (Wolverhampton), 31,523 audience (98% full)
Season: 2021-22, 24 round, 2022-02-10 19:45
0:1
(0:1)
| 25' |  | 0:1 | Gabriel Martinelli |
| 33' |  | Thomas Partey | |
| 36' | | Romain Saïss | |
| 45+1' | | Granit Xhaka | |
| 60' | | Rúben Neves | |
| 61' | | Gabriel Martinelli | |
| 69' |  | Gabriel Martinelli |
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