| 10 March 2022 | ||||||
| 19:30 | Norwich City |  | 1:3 |  | Chelsea |  |
| 18 March 2022 | ||||||
| 20:00 | Wolverhampton Wanderers |  | 2:3 |  | Leeds United | |
| 19 March 2022 | ||||||
| 12:30 | Aston Villa |  | 0:1 |  | Arsenal | |
| 20 March 2022 | ||||||
| 16:30 | Tottenham Hotspur |  | 3:1 |  | West Ham United | |
| 19 April 2022 | ||||||
| 20:00 | Liverpool |  | 4:0 |  | Manchester United | |
| 20 April 2022 | ||||||
| 20:00 | Manchester City |  | 3:0 |  | Brighton | |
| 21 April 2022 | ||||||
| 19:45 | Burnley |  | 2:0 |  | Southampton | |
| 11 May 2022 | ||||||
| 19:45 | Watford |  | 0:0 |  | Everton | |
| 07 August 2022 | ||||||
| 14:00 | Leicester City |  | 2:1 |  | Brentford | |
| 03 September 2022 | ||||||
| 15:00 | Newcastle United |  | 1:0 |  | Crystal Palace | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Manchester City | 29 | 22 | 4 | 3 | 68:18 | 70 |
| 2. |  | Liverpool | 29 | 21 | 6 | 2 | 75:20 | 69 |
| 3. |  | Chelsea | 28 | 17 | 8 | 3 | 57:19 | 59 |
| 4. |  | Arsenal | 28 | 17 | 3 | 8 | 44:31 | 54 |
| 5. |  | Tottenham Hotspur | 29 | 16 | 3 | 10 | 47:36 | 51 |
| 6. |  | Manchester United | 29 | 14 | 8 | 7 | 48:40 | 50 |
| 7. |  | West Ham United | 30 | 14 | 6 | 10 | 49:39 | 48 |
| 8. |  | Wolverhampton Wanderers | 30 | 14 | 4 | 12 | 31:26 | 46 |
| 9. |  | Aston Villa | 29 | 11 | 3 | 15 | 41:40 | 36 |
| 10. |  | Leicester City | 27 | 10 | 6 | 11 | 42:46 | 36 |
| 11. |  | Southampton | 29 | 8 | 11 | 10 | 36:45 | 35 |
| 12. |  | Crystal Palace | 29 | 7 | 13 | 9 | 39:38 | 34 |
| 13. |  | Brighton | 29 | 7 | 12 | 10 | 26:36 | 33 |
| 14. |  | Newcastle United | 29 | 7 | 10 | 12 | 32:49 | 31 |
| 15. |  | Brentford | 30 | 8 | 6 | 16 | 33:47 | 30 |
| 16. |  | Leeds United | 30 | 7 | 8 | 15 | 34:67 | 29 |
| 17. |  | Everton | 27 | 7 | 4 | 16 | 29:47 | 25 |
| 18. |  | Watford | 29 | 6 | 4 | 19 | 29:55 | 22 |
| 19. |  | Burnley | 27 | 3 | 12 | 12 | 22:38 | 21 |
| 20. |  | Norwich City | 29 | 4 | 5 | 20 | 18:63 | 17 |
Stadium: City of Manchester Stadium (Manchester), 52,226 audience (95% full)
Season: 2021-22, 30 round, 2022-04-20 20:00
3:0
(0:0)
| 53' |  | 1:0 | Riyad Mahrez |
| 65' | | 2:0 | Phil Foden |
| 79' |  | Alexis Mac Allister | |
| 81' | | Adam Webster | |
| 82' | | 3:0 | Bernardo Silva |
| 89' | | Lewis Dunk |
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