| 07 May 2022 | ||||||
| 15:00 | Brentford |  | 3:0 |  | Southampton |  |
| 15:00 | Burnley |  | 1:3 |  | Aston Villa | |
| 15:00 | Chelsea |  | 2:2 |  | Wolverhampton Wanderers | |
| 15:00 | Crystal Palace |  | 1:0 |  | Watford | |
| 17:30 | Brighton |  | 4:0 |  | Manchester United | |
| 19:45 | Liverpool |  | 1:1 |  | Tottenham Hotspur | |
| 08 May 2022 | ||||||
| 14:00 | Arsenal |  | 2:1 |  | Leeds United | |
| 14:00 | Leicester City |  | 1:2 |  | Everton | |
| 14:00 | Norwich City |  | 0:4 |  | West Ham United | |
| 16:30 | Manchester City |  | 5:0 |  | Newcastle United | |
Stadium: Falmer Stadium (Brighton and Hove), 31,637 audience (103% full)
Season: 2021-22, 36 round, 2022-05-07 17:30
4:0
(1:0)
| 15' |  | 1:0 | Moisés Caicedo |
| 45' |  | Cristiano Ronaldo | |
| 48' | | Diogo Dalot | |
| 49' | | 2:0 | Marc Cucurella |
| 57' | | 3:0 | Pascal Gross |
| 60' | | 4:0 | Leandro Trossard |
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