| 16 April 2021 | ||||||
| 20:00 | Everton |  | 2:2 |  | Tottenham Hotspur |  |
| 17 April 2021 | ||||||
| 20:15 | Wolverhampton Wanderers |  | 1:0 |  | Sheffield United | |
| 18 April 2021 | ||||||
| 13:30 | Arsenal |  | 1:1 |  | Fulham | |
| 16:00 | Manchester United |  | 3:1 |  | Burnley | |
| 19 April 2021 | ||||||
| 20:00 | Leeds United |  | 1:1 |  | Liverpool | |
| 20 April 2021 | ||||||
| 20:00 | Chelsea |  | 0:0 |  | Brighton | |
| 21 April 2021 | ||||||
| 20:15 | Aston Villa |  | 1:2 |  | Manchester City | |
| 22 April 2021 | ||||||
| 20:00 | Leicester City |  | 3:0 |  | WBA | |
| 11 May 2021 | ||||||
| 20:15 | Southampton |  | 3:1 |  | Crystal Palace | |
| 15 August 2021 | ||||||
| 14:00 | Newcastle United |  | 3:2 |  | West Ham United | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Manchester City | 33 | 24 | 5 | 4 | 69:24 | 77 |
| 2. |  | Manchester United | 32 | 19 | 9 | 4 | 64:35 | 66 |
| 3. |  | Leicester City | 32 | 18 | 5 | 9 | 58:37 | 59 |
| 4. |  | Chelsea | 32 | 15 | 10 | 7 | 50:31 | 55 |
| 5. |  | West Ham United | 32 | 16 | 7 | 9 | 53:42 | 55 |
| 6. |  | Tottenham Hotspur | 33 | 15 | 8 | 10 | 56:38 | 53 |
| 7. |  | Liverpool | 32 | 15 | 8 | 9 | 54:38 | 53 |
| 8. |  | Everton | 31 | 14 | 7 | 10 | 43:40 | 49 |
| 9. |  | Arsenal | 32 | 13 | 7 | 12 | 44:36 | 46 |
| 10. |  | Leeds United | 32 | 14 | 4 | 14 | 50:50 | 46 |
| 11. |  | Aston Villa | 31 | 13 | 5 | 13 | 44:35 | 44 |
| 12. |  | Wolverhampton Wanderers | 32 | 11 | 8 | 13 | 32:41 | 41 |
| 13. |  | Crystal Palace | 31 | 10 | 8 | 13 | 33:52 | 38 |
| 14. |  | Southampton | 32 | 10 | 6 | 16 | 40:58 | 36 |
| 15. |  | Newcastle United | 32 | 9 | 8 | 15 | 35:53 | 35 |
| 16. |  | Brighton | 32 | 7 | 13 | 12 | 33:38 | 34 |
| 17. |  | Burnley | 32 | 8 | 9 | 15 | 26:45 | 33 |
| 18. |  | Fulham | 33 | 5 | 12 | 16 | 25:43 | 27 |
| 19. |  | WBA | 32 | 5 | 9 | 18 | 28:62 | 24 |
| 20. |  | Sheffield United | 32 | 4 | 2 | 26 | 17:56 | 14 |
Stadium: St Mary's Stadium (Southampton)
Season: 2020-21, 32 round, 2021-05-11 20:15
3:1
(1:1)
| 2' |  | 0:1 | Christian Benteke |
| 19' | | 1:1 | Danny Ings |
| 44' |  | Jan Bednarek | |
| 45+1' | | Jordan Ayew | |
| 48' | | 2:1 | Che Adams |
| 55' | | Jannik Vestergaard | |
| 75' | | 3:1 | Danny Ings |
| 77' | | Cheikhou Kouyaté | |
| 90+2' | | Wilfried Zaha |
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