| 27 August 2022 | ||||||
| 12:30 | Southampton |  | 0:1 |  | Manchester United |  |
| 15:00 | Brentford |  | 1:1 |  | Everton | |
| 15:00 | Brighton |  | 1:0 |  | Leeds United | |
| 15:00 | Chelsea |  | 2:1 |  | Leicester City | |
| 15:00 | Liverpool |  | 9:0 |  | Bournemouth | |
| 15:00 | Manchester City |  | 4:2 |  | Crystal Palace | |
| 17:30 | Arsenal |  | 2:1 |  | Fulham | |
| 28 August 2022 | ||||||
| 14:00 | Aston Villa |  | 0:1 |  | West Ham United | |
| 14:00 | Wolverhampton Wanderers |  | 1:1 |  | Newcastle United | |
| 16:30 | Nottingham Forest |  | 0:2 |  | Tottenham Hotspur | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Arsenal | 4 | 4 | 0 | 0 | 11:3 | 12 |
| 2. |  | Manchester City | 4 | 3 | 1 | 0 | 13:5 | 10 |
| 3. |  | Tottenham Hotspur | 4 | 3 | 1 | 0 | 9:3 | 10 |
| 4. |  | Brighton | 4 | 3 | 1 | 0 | 5:1 | 10 |
| 5. |  | Leeds United | 4 | 2 | 1 | 1 | 7:4 | 7 |
| 6. |  | Chelsea | 4 | 2 | 1 | 1 | 5:6 | 7 |
| 7. |  | Newcastle United | 4 | 1 | 3 | 0 | 6:4 | 6 |
| 8. |  | Manchester United | 4 | 2 | 0 | 2 | 4:7 | 6 |
| 9. |  | Liverpool | 4 | 1 | 2 | 1 | 13:5 | 5 |
| 10. |  | Brentford | 4 | 1 | 2 | 1 | 9:6 | 5 |
| 11. |  | Fulham | 4 | 1 | 2 | 1 | 6:6 | 5 |
| 12. |  | Crystal Palace | 4 | 1 | 1 | 2 | 6:8 | 4 |
| 13. |  | Southampton | 4 | 1 | 1 | 2 | 5:8 | 4 |
| 14. |  | Nottingham Forest | 4 | 1 | 1 | 2 | 2:5 | 4 |
| 15. |  | Aston Villa | 4 | 1 | 0 | 3 | 3:7 | 3 |
| 16. |  | West Ham United | 4 | 1 | 0 | 3 | 1:5 | 3 |
| 17. |  | Bournemouth | 4 | 1 | 0 | 3 | 2:16 | 3 |
| 18. |  | Everton | 4 | 0 | 2 | 2 | 3:5 | 2 |
| 19. |  | Wolverhampton Wanderers | 4 | 0 | 2 | 2 | 2:4 | 2 |
| 20. |  | Leicester City | 4 | 0 | 1 | 3 | 6:10 | 1 |
Stadium: St Mary's Stadium (Southampton), 31,196 audience (95% full)
Season: 2022-23, 4 round, 2022-08-27 12:30
0:1
(0:0)
| 50' |  | Diogo Dalot | |
| 55' |  | 0:1 | Bruno Fernandes |
| 83' | | Scott McTominay | |
| 90+6' | | David de Gea |
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