| 30 November 2021 | ||||||
| 19:30 | Newcastle United |  | 1:1 |  | Norwich City |  |
| 20:15 | Leeds United |  | 1:0 |  | Crystal Palace | |
| 01 December 2021 | ||||||
| 19:30 | Watford |  | 1:2 |  | Chelsea | |
| 19:30 | Wolverhampton Wanderers |  | 0:0 |  | Burnley | |
| 19:30 | Southampton |  | 2:2 |  | Leicester City | |
| 02 December 2021 | ||||||
| 19:30 | Tottenham Hotspur |  | 2:0 |  | Brentford | |
| 21 August 2022 | ||||||
| 14:00 | West Ham United |  | 1:1 |  | Brighton | |
| 03 September 2022 | ||||||
| 12:30 | Everton |  | 1:4 |  | Liverpool | |
| 17:30 | Aston Villa |  | 1:2 |  | Manchester City | |
| 04 September 2022 | ||||||
| 16:30 | Manchester United |  | 3:2 |  | Arsenal | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Chelsea | 14 | 10 | 3 | 1 | 33:6 | 33 |
| 2. |  | Manchester City | 14 | 10 | 2 | 2 | 29:8 | 32 |
| 3. |  | Liverpool | 14 | 9 | 4 | 1 | 43:12 | 31 |
| 4. |  | West Ham United | 14 | 7 | 3 | 4 | 25:17 | 24 |
| 5. |  | Arsenal | 14 | 7 | 2 | 5 | 17:20 | 23 |
| 6. |  | Tottenham Hotspur | 13 | 7 | 1 | 5 | 13:17 | 22 |
| 7. |  | Manchester United | 14 | 6 | 3 | 5 | 24:24 | 21 |
| 8. |  | Wolverhampton Wanderers | 14 | 6 | 3 | 5 | 12:12 | 21 |
| 9. |  | Brighton | 14 | 4 | 7 | 3 | 13:15 | 19 |
| 10. |  | Leicester City | 14 | 5 | 4 | 5 | 22:25 | 19 |
| 11. |  | Crystal Palace | 14 | 3 | 7 | 4 | 19:20 | 16 |
| 12. |  | Brentford | 14 | 4 | 4 | 6 | 17:19 | 16 |
| 13. |  | Aston Villa | 14 | 5 | 1 | 8 | 19:23 | 16 |
| 14. |  | Everton | 14 | 4 | 3 | 7 | 17:24 | 15 |
| 15. |  | Leeds United | 14 | 3 | 6 | 5 | 13:20 | 15 |
| 16. |  | Southampton | 14 | 3 | 6 | 5 | 13:20 | 15 |
| 17. |  | Watford | 14 | 4 | 1 | 9 | 19:26 | 13 |
| 18. |  | Burnley | 13 | 1 | 7 | 5 | 14:20 | 10 |
| 19. |  | Norwich City | 14 | 2 | 4 | 8 | 8:28 | 10 |
| 20. |  | Newcastle United | 14 | 0 | 7 | 7 | 16:30 | 7 |
Stadium: Old Trafford (Manchester), 73,123 audience (97% full)
Season: 2021-22, 14 round, 2022-09-04 16:30
3:2
(1:1)
| 13' |  | 0:1 | Emile Smith Rowe |
| 44' | | 1:1 | Bruno Fernandes |
| 45+1' |  | Scott McTominay | |
| 52' | | 2:1 | Cristiano Ronaldo |
| 54' | | 2:2 | Martin Odegaard |
| 70' |  | 3:2 | Cristiano Ronaldo |
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