| 28 December 2020 | ||||||
| 15:00 | Crystal Palace |  | 1:1 |  | Leicester City |  |
| 17:30 | Chelsea |  | 1:1 |  | Aston Villa | |
| 29 December 2020 | ||||||
| 18:00 | Brighton |  | 0:1 |  | Arsenal | |
| 18:00 | Burnley |  | 1:0 |  | Sheffield United | |
| 18:00 | Southampton |  | 0:0 |  | West Ham United | |
| 18:00 | WBA |  | 0:5 |  | Leeds United | |
| 20:00 | Manchester United |  | 1:0 |  | Wolverhampton Wanderers | |
| 30 December 2020 | ||||||
| 20:00 | Newcastle United |  | 0:0 |  | Liverpool | |
| 16 January 2021 | ||||||
| 20:15 | Tottenham Hotspur |  | 1:1 |  | Fulham | |
| 17 February 2021 | ||||||
| 20:15 | Everton |  | 1:3 |  | Manchester City | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Liverpool | 16 | 9 | 6 | 1 | 37:20 | 33 |
| 2. |  | Manchester United | 15 | 9 | 3 | 3 | 31:23 | 30 |
| 3. |  | Leicester City | 16 | 9 | 2 | 5 | 29:20 | 29 |
| 4. |  | Everton | 15 | 9 | 2 | 4 | 26:19 | 29 |
| 5. |  | Aston Villa | 14 | 8 | 2 | 4 | 28:14 | 26 |
| 6. |  | Chelsea | 16 | 7 | 5 | 4 | 31:18 | 26 |
| 7. |  | Tottenham Hotspur | 15 | 7 | 5 | 3 | 26:15 | 26 |
| 8. |  | Manchester City | 14 | 7 | 5 | 2 | 21:12 | 26 |
| 9. |  | Southampton | 16 | 7 | 5 | 4 | 25:19 | 26 |
| 10. |  | West Ham United | 16 | 6 | 5 | 5 | 23:21 | 23 |
| 11. |  | Leeds United | 16 | 7 | 2 | 7 | 30:30 | 23 |
| 12. |  | Wolverhampton Wanderers | 16 | 6 | 3 | 7 | 15:21 | 21 |
| 13. |  | Arsenal | 16 | 6 | 2 | 8 | 16:19 | 20 |
| 14. |  | Newcastle United | 15 | 5 | 4 | 6 | 17:24 | 19 |
| 15. |  | Crystal Palace | 16 | 5 | 4 | 7 | 20:29 | 19 |
| 16. |  | Burnley | 15 | 4 | 4 | 7 | 9:20 | 16 |
| 17. |  | Brighton | 16 | 2 | 7 | 7 | 18:25 | 13 |
| 18. |  | Fulham | 15 | 2 | 5 | 8 | 13:23 | 11 |
| 19. |  | WBA | 16 | 1 | 5 | 10 | 11:35 | 8 |
| 20. |  | Sheffield United | 16 | 0 | 2 | 14 | 8:27 | 2 |
Stadium: Tottenham Hotspur (London)
Season: 2020-21, 16 round, 2021-01-16 20:15
1:1
(1:0)
| 18' |  | Andre-Frank Zambo Anguissa | |
| 25' |  | 1:0 | Harry Kane |
| 64' | | Pierre Emile Hojbjerg | |
| 74' | | 1:1 | Ivan Cavaleiro |
| 90+2' | | Joachim Andersen |
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