Full statistics between Manchester United and Southampton
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Arsenal | 38 | 23 | 9 | 6 | 68:33 | 78 |
| 2. |  | Manchester United | 38 | 23 | 8 | 7 | 73:26 | 77 |
| 3. |  | Liverpool | 38 | 18 | 11 | 9 | 68:42 | 65 |
| 4. |  | Chelsea | 38 | 20 | 3 | 15 | 71:43 | 63 |
| 5. |  | Leeds United | 38 | 17 | 8 | 13 | 57:46 | 59 |
| 6. |  | Blackburn Rovers | 38 | 16 | 10 | 12 | 57:52 | 58 |
| 7. |  | Aston Villa | 38 | 17 | 6 | 15 | 49:48 | 57 |
| 8. |  | West Ham United | 38 | 16 | 8 | 14 | 56:57 | 56 |
| 9. |  | Derby County | 38 | 16 | 7 | 15 | 52:49 | 55 |
| 10. |  | Leicester City | 38 | 13 | 14 | 11 | 51:41 | 53 |
| 11. |  | Coventry City | 38 | 12 | 16 | 10 | 46:44 | 52 |
| 12. |  | Southampton | 38 | 14 | 6 | 18 | 50:55 | 48 |
| 13. |  | Newcastle United | 38 | 11 | 11 | 16 | 35:44 | 44 |
| 14. |  | Tottenham Hotspur | 38 | 11 | 11 | 16 | 44:56 | 44 |
| 15. |  | Wimbledon | 38 | 10 | 14 | 14 | 34:46 | 44 |
| 16. |  | Sheffield Wednesday | 38 | 12 | 8 | 18 | 52:67 | 44 |
| 17. |  | Everton | 38 | 9 | 13 | 16 | 41:56 | 40 |
| 18. |  | Bolton Wanderers | 38 | 9 | 13 | 16 | 41:61 | 40 |
| 19. |  | Barnsley | 38 | 10 | 5 | 23 | 37:82 | 35 |
| 20. |  | Crystal Palace | 38 | 8 | 9 | 21 | 37:71 | 33 |
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