Full statistics between Manchester United and Southampton
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Arsenal | 38 | 24 | 13 | 1 | 74:18 | 83 |
| 2. |  | Liverpool | 38 | 23 | 7 | 8 | 77:40 | 76 |
| 3. |  | Crystal Palace | 38 | 20 | 9 | 9 | 50:41 | 69 |
| 4. |  | Leeds United | 38 | 19 | 7 | 12 | 65:47 | 64 |
| 5. |  | Manchester City | 38 | 17 | 11 | 10 | 64:53 | 62 |
| 6. |  | Manchester United | 38 | 16 | 12 | 10 | 58:45 | 59 |
| 7. |  | Wimbledon | 38 | 14 | 14 | 10 | 53:46 | 56 |
| 8. |  | Nottingham Forest | 38 | 14 | 12 | 12 | 65:50 | 54 |
| 9. |  | Everton | 38 | 13 | 12 | 13 | 50:46 | 51 |
| 10. |  | Tottenham Hotspur | 38 | 11 | 16 | 11 | 51:50 | 49 |
| 11. |  | Chelsea | 38 | 13 | 10 | 15 | 58:69 | 49 |
| 12. |  | Queens Park Rangers | 38 | 12 | 10 | 16 | 44:53 | 46 |
| 13. |  | Sheffield United | 38 | 13 | 7 | 18 | 36:55 | 46 |
| 14. |  | Southampton | 38 | 12 | 9 | 17 | 58:69 | 45 |
| 15. |  | Norwich City | 38 | 13 | 6 | 19 | 41:64 | 45 |
| 16. |  | Coventry City | 38 | 11 | 11 | 16 | 42:49 | 44 |
| 17. |  | Aston Villa | 38 | 9 | 14 | 15 | 46:58 | 41 |
| 18. |  | Luton Town | 38 | 10 | 7 | 21 | 42:61 | 37 |
| 19. |  | Sunderland | 38 | 8 | 10 | 20 | 38:60 | 34 |
| 20. |  | Derby County | 38 | 5 | 9 | 24 | 37:75 | 24 |
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