Full statistics between Manchester United and Southampton
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Manchester United | 38 | 21 | 12 | 5 | 76:44 | 75 |
| 2. |  | Newcastle United | 38 | 19 | 11 | 8 | 73:40 | 68 |
| 3. |  | Arsenal | 38 | 19 | 11 | 8 | 62:32 | 68 |
| 4. |  | Liverpool | 38 | 19 | 11 | 8 | 62:37 | 68 |
| 5. |  | Aston Villa | 38 | 17 | 10 | 11 | 47:34 | 61 |
| 6. |  | Chelsea | 38 | 16 | 11 | 11 | 58:55 | 59 |
| 7. |  | Sheffield Wednesday | 38 | 14 | 15 | 9 | 50:51 | 57 |
| 8. |  | Wimbledon | 38 | 15 | 11 | 12 | 49:46 | 56 |
| 9. |  | Leicester City | 38 | 12 | 11 | 15 | 46:54 | 47 |
| 10. |  | Tottenham Hotspur | 38 | 13 | 7 | 18 | 44:51 | 46 |
| 11. |  | Leeds United | 38 | 11 | 13 | 14 | 28:38 | 46 |
| 12. |  | Derby County | 38 | 11 | 13 | 14 | 45:58 | 46 |
| 13. |  | Blackburn Rovers | 38 | 9 | 15 | 14 | 42:43 | 42 |
| 14. |  | West Ham United | 38 | 10 | 12 | 16 | 39:48 | 42 |
| 15. |  | Everton | 38 | 10 | 12 | 16 | 44:57 | 42 |
| 16. |  | Southampton | 38 | 10 | 11 | 17 | 50:56 | 41 |
| 17. |  | Coventry City | 38 | 9 | 14 | 15 | 38:54 | 41 |
| 18. |  | Sunderland | 38 | 10 | 10 | 18 | 35:53 | 40 |
| 19. |  | Middlesbrough | 38 | 10 | 12 | 16 | 51:60 | 39 |
| 20. |  | Nottingham Forest | 38 | 6 | 16 | 16 | 31:59 | 34 |
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