| 21 January 2022 | ||||||
| 20:00 | Watford |  | 0:3 |  | Norwich City |  |
| 22 January 2022 | ||||||
| 12:30 | Everton |  | 0:1 |  | Aston Villa | |
| 15:00 | Brentford |  | 1:2 |  | Wolverhampton Wanderers | |
| 15:00 | Leeds United |  | 0:1 |  | Newcastle United | |
| 15:00 | Manchester United |  | 1:0 |  | West Ham United | |
| 17:30 | Southampton |  | 1:1 |  | Manchester City | |
| 23 January 2022 | ||||||
| 14:00 | Arsenal |  | 0:0 |  | Burnley | |
| 14:00 | Crystal Palace |  | 1:3 |  | Liverpool | |
| 14:00 | Leicester City |  | 1:1 |  | Brighton | |
| 14 August 2022 | ||||||
| 16:30 | Chelsea |  | 2:0 |  | Tottenham Hotspur | |
Stadium: St Mary's Stadium (Southampton), 31,178 audience (95% full)
Season: 2021-22, 23 round, 2022-01-22 17:30
1:1
(1:0)
| 7' |  | 1:0 | Kyle Walker-Peters |
| 33' |  | Jan Bednarek | |
| 65' | | 1:1 | Aymeric Laporte |
| 79' | | Adam Armstrong | |
| 90+2' | | Mohamed Elyounoussi |
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