| 08 April 2022 | ||||||
| 20:00 | Newcastle United |  | 1:0 |  | Wolverhampton Wanderers |  |
| 09 April 2022 | ||||||
| 12:30 | Everton |  | 1:0 |  | Manchester United | |
| 15:00 | Arsenal |  | 1:2 |  | Brighton | |
| 15:00 | Watford |  | 0:3 |  | Leeds United | |
| 17:30 | Aston Villa |  | 0:4 |  | Tottenham Hotspur | |
| 10 April 2022 | ||||||
| 14:00 | Brentford |  | 2:0 |  | West Ham United | |
| 14:00 | Leicester City |  | 2:1 |  | Crystal Palace | |
| 14:00 | Norwich City |  | 2:0 |  | Burnley | |
| 16:30 | Manchester City |  | 2:2 |  | Liverpool | |
| 30 August 2022 | ||||||
| 19:45 | Southampton |  | 0:6 |  | Chelsea | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Manchester City | 30 | 23 | 4 | 3 | 70:18 | 73 |
| 2. |  | Liverpool | 30 | 22 | 6 | 2 | 77:20 | 72 |
| 3. |  | Chelsea | 30 | 18 | 8 | 4 | 64:23 | 62 |
| 4. |  | Tottenham Hotspur | 31 | 18 | 3 | 10 | 56:37 | 57 |
| 5. |  | Arsenal | 30 | 17 | 3 | 10 | 45:36 | 54 |
| 6. |  | West Ham United | 31 | 15 | 6 | 10 | 51:40 | 51 |
| 7. |  | Manchester United | 31 | 14 | 9 | 8 | 49:42 | 51 |
| 8. |  | Wolverhampton Wanderers | 32 | 15 | 4 | 13 | 33:28 | 49 |
| 9. |  | Crystal Palace | 30 | 8 | 13 | 9 | 42:38 | 37 |
| 10. |  | Leicester City | 28 | 10 | 7 | 11 | 43:47 | 37 |
| 11. |  | Brighton | 31 | 8 | 13 | 10 | 28:37 | 37 |
| 12. |  | Aston Villa | 31 | 11 | 3 | 17 | 42:46 | 36 |
| 13. |  | Southampton | 31 | 8 | 12 | 11 | 37:52 | 36 |
| 14. |  | Newcastle United | 31 | 8 | 10 | 13 | 34:54 | 34 |
| 15. |  | Brentford | 31 | 9 | 6 | 16 | 37:48 | 33 |
| 16. |  | Leeds United | 32 | 8 | 9 | 15 | 38:68 | 33 |
| 17. |  | Everton | 30 | 8 | 4 | 18 | 33:52 | 28 |
| 18. |  | Burnley | 29 | 4 | 12 | 13 | 25:42 | 24 |
| 19. |  | Watford | 31 | 6 | 4 | 21 | 29:60 | 22 |
| 20. |  | Norwich City | 30 | 4 | 6 | 20 | 18:63 | 18 |
Stadium: St Mary's Stadium (Southampton), 32,000 audience (98% full)
Season: 2021-22, 32 round, 2022-08-30 19:45
0:6
(0:4)
| 8' |  | 0:1 | Marcos Alonso |
| 16' | | 0:2 | Mason Mount |
| 21' | | 0:3 | Timo Werner |
| 31' | | 0:4 | Kai Havertz |
| 49' | | 0:5 | Timo Werner |
| 54' | | 0:6 | Mason Mount |
| 60' |  | Jan Bednarek |
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