Full statistics between Manchester United and Southampton
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Arsenal | 38 | 26 | 9 | 3 | 79:36 | 87 |
| 2. |  | Liverpool | 38 | 24 | 8 | 6 | 67:30 | 80 |
| 3. |  | Manchester United | 38 | 24 | 5 | 9 | 87:45 | 77 |
| 4. |  | Newcastle United | 38 | 21 | 8 | 9 | 74:52 | 71 |
| 5. |  | Leeds United | 38 | 18 | 12 | 8 | 53:37 | 66 |
| 6. |  | Chelsea | 38 | 17 | 13 | 8 | 66:38 | 64 |
| 7. |  | West Ham United | 38 | 15 | 8 | 15 | 48:57 | 53 |
| 8. |  | Aston Villa | 38 | 12 | 14 | 12 | 46:47 | 50 |
| 9. |  | Tottenham Hotspur | 38 | 14 | 8 | 16 | 49:53 | 50 |
| 10. |  | Blackburn Rovers | 38 | 12 | 10 | 16 | 55:51 | 46 |
| 11. |  | Southampton | 38 | 12 | 9 | 17 | 46:54 | 45 |
| 12. |  | Middlesbrough | 38 | 12 | 9 | 17 | 35:47 | 45 |
| 13. |  | Fulham | 38 | 10 | 14 | 14 | 36:44 | 44 |
| 14. |  | Charlton Athletic | 38 | 10 | 14 | 14 | 38:49 | 44 |
| 15. |  | Everton | 38 | 11 | 10 | 17 | 45:57 | 43 |
| 16. |  | Bolton Wanderers | 38 | 9 | 13 | 16 | 44:62 | 40 |
| 17. |  | Sunderland | 38 | 10 | 10 | 18 | 29:51 | 40 |
| 18. |  | Ipswich Town | 38 | 9 | 9 | 20 | 41:64 | 36 |
| 19. |  | Derby County | 38 | 8 | 6 | 24 | 33:63 | 30 |
| 20. |  | Leicester City | 38 | 5 | 13 | 20 | 30:64 | 28 |
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