| 28 April 2022 | ||||||
| 19:45 | Manchester United |  | 1:1 |  | Chelsea |  |
| 15 May 2022 | ||||||
| 12:00 | Tottenham Hotspur |  | 1:0 |  | Burnley | |
| 14:00 | Aston Villa |  | 1:1 |  | Crystal Palace | |
| 14:00 | Leeds United |  | 1:1 |  | Brighton | |
| 14:00 | Watford |  | 1:5 |  | Leicester City | |
| 14:00 | Wolverhampton Wanderers |  | 1:1 |  | Norwich City | |
| 16:30 | Everton |  | 2:3 |  | Brentford | |
| 16 May 2022 | ||||||
| 20:00 | Newcastle United |  | 2:0 |  | Arsenal | |
| 17 May 2022 | ||||||
| 19:45 | Southampton |  | 1:2 |  | Liverpool | |
| 07 August 2022 | ||||||
| 16:30 | West Ham United |  | 2:2 |  | Manchester City | |
| # | Club | T | W | D | L | GD | P | |
| 1. |  | Manchester City | 37 | 28 | 6 | 3 | 96:24 | 90 |
| 2. |  | Liverpool | 37 | 27 | 8 | 2 | 91:25 | 89 |
| 3. |  | Chelsea | 37 | 20 | 11 | 6 | 74:32 | 71 |
| 4. |  | Tottenham Hotspur | 37 | 21 | 5 | 11 | 64:40 | 68 |
| 5. |  | Arsenal | 37 | 21 | 3 | 13 | 56:47 | 66 |
| 6. |  | Manchester United | 37 | 16 | 10 | 11 | 57:56 | 58 |
| 7. |  | West Ham United | 37 | 16 | 8 | 13 | 59:48 | 56 |
| 8. |  | Wolverhampton Wanderers | 37 | 15 | 6 | 16 | 37:40 | 51 |
| 9. |  | Leicester City | 37 | 13 | 10 | 14 | 58:58 | 49 |
| 10. |  | Brighton | 37 | 11 | 15 | 11 | 39:43 | 48 |
| 11. |  | Brentford | 37 | 13 | 7 | 17 | 47:54 | 46 |
| 12. |  | Newcastle United | 37 | 12 | 10 | 15 | 42:61 | 46 |
| 13. |  | Crystal Palace | 37 | 10 | 15 | 12 | 49:46 | 45 |
| 14. |  | Aston Villa | 37 | 13 | 6 | 18 | 50:51 | 45 |
| 15. |  | Southampton | 37 | 9 | 13 | 15 | 42:63 | 40 |
| 16. |  | Everton | 37 | 11 | 6 | 20 | 42:61 | 39 |
| 17. |  | Burnley | 37 | 7 | 14 | 16 | 33:51 | 35 |
| 18. |  | Leeds United | 37 | 8 | 11 | 18 | 40:78 | 35 |
| 19. |  | Watford | 37 | 6 | 5 | 26 | 33:75 | 23 |
| 20. |  | Norwich City | 37 | 5 | 7 | 25 | 23:79 | 22 |
Stadium: London Stadium (London), 59,972 audience (100% full)
Season: 2021-22, 37 round, 2022-08-07 16:30
2:2
(2:0)
| 24' |  | 1:0 | Jarrod Bowen |
| 32' |  | Jarrod Bowen | |
| 45' | | 2:0 | Jarrod Bowen |
| 49' | | 2:1 | Jack Grealish |
| 58' | | Vladimír Coufal | |
| 60' | | Lukasz Fabiański | |
| 69' | | 2:2 | Vladimír Coufal |
| 90+4' | | Gabriel Jesus |
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